WebDARS is a parallel group, phase III, multicentre, randomised-controlled radiotherapy trial to determine if dysphagia optimised intensity modulated radiotherapy (Do-IMRT) … WebJun 17, 2024 · However, DO-IMRT, which has been pioneered by researchers from The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, is optimised to reduce the risk of swallowing difficulties, known as dysphagia. It does this by reducing radiation to the pharyngeal muscles, which support swallowing.
DARS - The Institute of Cancer Research, London
WebJun 1, 2024 · A new optimised intensity-modulated radiation therapy (IMRT) pioneered at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research, London, has been shown to spare head and neck cancer patients’ adverse life-long side effects post treatment. The initial results from the Dysphagia-Aspiration Related Structures (DARS) … Websparing strategies. The aim of Dysphagia/Aspiration at risk structures (DARS) trial is to determine whether reducing the dose to the pharyngeal constrictors with dysphagia-optimised intensity- modulated radiotherapy (Do-IMRT) will lead to an improvement in long- term swallowing function without having any detrimental impact on disease- cscc my schedule
DARS: a phase III randomised multicentre study of …
WebNov 1, 2015 · In this review, we discuss the swallowing structures responsible for functional impairment, analyse the studies that have explored the dose–response relationship between these critical structures and late dysphagia, and consider the merits of reported dysphagia-optimised IMRT (Do-IMRT) approaches, thus far. WebOct 26, 2024 · Swallowing difficulty is a significant side effect for people who have been treated with radiation for head and neck cancer (HNC) [1,2]. Dysphagia-optimised intensity modulated radiotherapy (DO-IMRT) has been shown to reduce dysphagia within a multicentre randomised controlled trial (RCT) by reducing dose to pharyngeal constrictor … WebFeb 24, 2024 · The preferential sparing achievable with intensity-modulated radiotherapy (IMRT) of key swallowing structures implicated in post-radiation dysfunction, such as the … csc code for south africa