Hif-1α抗体

Web360 linhas · HIF-1 alpha (clone H1alpha67) was used at 1:500 dilution for WB assays in lysates from human glioblastoma cell lines U87MG and T98G which were left untransfected or transfected with empty vector (Control shRNA) or with Parkin shRNA (Parkin shRNA) … PC12 whole cell lysate is provided as a Western blot positive control. The … Nuclear HIF-1 engages p300/CBP for binding to hypoxic response elements … L929 cells are grown under standard tissue culture conditions until semi-confluent … There are currently no images for Raw 264.7 Lysate (NBP3-11860). Every … Publications using NB200-103 Applications Species; Reis-Barbosa PH, Marinho TS, … Publications using NB300-605 Applications Species; Janani G, Zhang L, Badylak S … CoCl2 inhibits prolyl-hydroxylases (PHD enzymes), the oxygen sensors, through … PHD2/HIF Prolyl Hydroxylase 2 antibody used for WB at 1 : 500 dilution on 30 … WebMinimal reactivity occurs with the non-hydroxylated form of the protein. This antibody is specific for HIF-1a hydroxylated at P564. Minimal cross-reactivity occurs with non …

HIF-1 alpha パスウェイ アブカム - Abcam

WebWestern blot analysis of HIF-1α on lysate from HeLa stimulated with CoCl2, cobalt chloride. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the Mouse Anti- Human HIF-1α antibody. ... 抗体 の詳細. 54/HIF-1α ... WebSummary. HIF1 alpha antibody recognizes HIF1 alpha (HIF1a) protein, which is a subunit of the heterodimeric transcription factor hypoxia … immigration attorney in northern virginia https://jtcconsultants.com

HIF-1 α 抗体 SCBT - Santa Cruz Biotechnology

WebWe show that ABL kinases phosphorylate and interact with CUL4A, a cullin ring ligase adaptor, and compete with CPSF1 for CUL4A binding, leading to increased HIF-1α … Web23 de jul. de 2024 · HIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … WebHIF-1α Antibody 可检测 HIF-1α 总蛋白的内源水平。 该抗体在生理条件不与其他家族成员发生交叉反应，并且不会检测显著水平的羟化 HIF-1α。 物种反应性： immigration attorney in odessa texas

Purified Mouse Anti-Human HIF-1α - BD Biosciences

Category:HIF-1alpha/HIF1A Mouse Monoclonal Antibody (HIF …

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Hif-1α抗体

壹生资讯-肿瘤微环境与肝癌干细胞相互作用对肝细胞 ...

Web31 de mai. de 2024 · 相关文献显示，hif-α在正常环境下不易被检测到，仅少量可进入胞核并结合hif-1β进而产生hif-1复合物而发挥重要作用。 临床研究报道，HIF-1α可通过激活诸多类型基因表达进而作用于糖酵解、葡萄糖摄取等过程。 WebHIF-1α Antibody (28b) is an IgG 1 κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the detection of the HIF …

Hif-1α抗体

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Web缺氧诱导因子-1α(hypoxia-inducible factor 1α, HIF-1α)属于氧依赖的转录激活因子，在缺氧条件下HIF-1α的转录水平升高，参与肿瘤的生长及侵袭过程[4]。肺腺癌的靶向治疗目前已取得突破性进展，但仍有部分患者不能采用靶向治疗，对于这部分患者我们需要探索新的方法。 WebHIF-1 is a heterodimeric protein complex composed of two subunits; one constitutively stable and expressed HIF1β, and the other inducible by O 2 and growth factors, HIF-1α. …

Web抗HIF抗体(Anti-HIF-1/HIF-2 antibody)をご紹介しています。低酸素誘導因子(Hypoxia Inducible Factor, HIF)は哺乳動物細胞に見られる転写因子で，細胞の低酸素応答の指標として創薬分野などで注目されています。 Webhif-1αは、通常の酸素状態の間は、プロリン残基402と506でヒドロキシル化され、すぐにユビキチン化され、プロテアソームにより分解されます。 しかしながら、低酸素状態では、プロリンのヒドロキシル化が減少するため、HIF-1α分子の分解は防止されます。

WebHIF-1α抗体(小鼠单抗) AG2258. 50μl. IL-1β Mouse Monoclonal Antibody. AG2111. 50μl. Phospho-Histone H1.B (Thr146) Rabbit Polyclonal Antibody. AF1837. 50μl. HIF-1 beta Rabbit Monoclonal Antibody. Web近年来肝癌的发病率有所上升，尤其是肝细胞癌(HCC)，而肝癌干细胞(liver cancer stem cells，LCSC)在HCC的发生发展中起着关键作用[1]。LCSC又称为肝癌起动细胞，是一类能自我更新并分化形成肿瘤的细胞，它引发H

Web11 de abr. de 2024 · 该团队通过分析多种肿瘤细胞高频缺失的染色体位点，鉴定出了一个具有潜在抑癌活性的lncRNA基因，并将其命名为 HITT（HIF-1α inhibitor at translation level）。前期研究发现HITT可对低氧，DNA损伤等应激因素作出应答，HITT低表达的肿瘤细胞表现为应激压力下的生存优势。

Web中文名： 大鼠低氧诱导因子1α (HIF-1α)ELISA Kit 查看详情 >>. 英文名：Rat hypoxia-inducible factor 1α,HIF-1α ELISA Kit. 别名：相关类别：ELISA. 储存条件：2-8℃. 产品编号：kt20301货号：69-20301. 中文名： 人胎盘核糖核酸抑止剂 (HPRI)ELISA Kit 查看详情 >>. 英文名：Human placental ... list of sydney suburbs by regionWebAll lanes : Anti-HIF-1 alpha antibody [H1alpha67] (ab1) at 5 µg/ml Lane 1 : HeLa nuclear extract lysate at 40 µg Lane 2 : Hela-DFO treated (0.5mM, 24h) Nuclear Lysate at 40 µg Lane 3 : HeLa nuclear control at 40 µg Lane 4 : HeLa nuclear DFO treated at 40 µg Lane 5 : Recombinant Human HIF-1 alpha protein at 0.001 µg immigration attorney intake formWeb）hif-1α同泛素结合，需要e1、e2、e3酶相互传递，最终为靶蛋白加上泛素（泛素化）。 还可以在泛素上面加泛素（因为泛素蛋白自己身上也有泛素化位点），这样可以加上一条长长的泛素链，然后将靶蛋白引向蛋白酶体，蛋白酶体将其“粉碎”水解。 immigration attorney in oxnard caWeb您可以从下面列出的单克隆抗体中挑选hif-1 α抗体。点击进入产品详情页查看hif-1 α抗体的详细信息。 根据抗体亚型、抗原决定簇、应用和物种反应性，挑选适合您研究的hif-1 α抗 … immigration attorney in orlando flWebProduct Description. Hypoxia-inducible factor- 1α (HIF- 1α) is a transcription factor that accumulates under low- oxygen conditions. 1, 2 Following hypoxic stimulus and … immigration attorney in tucsonWeb本HIF-1α抗体(HIF-1α antibody)为进口分装，以人HIF-1αaa432-528一段多肽为抗原制备的小鼠单克隆抗体，然后用protein A和抗原亲和柱经过两步纯化得到的高纯度抗体。克隆号 … immigration attorney in orlando floridaWebNuclear HIF-1 engages p300/CBP for binding to hypoxic response elements (HREs). This process induces transcription and regulation of genes including EPO, VEGF, iNOS2, ANGPT1 and OCT4 (4,5). Under normoxic conditions, the HIF-1 alpha subunit is rapidly targeted and degraded by the ubiquitin proteasome system. immigration attorney in worcester